import math import matplotlib.pyplot as plt import numpy as np from graph_tool.all import * from src import centrality from src import plot from src import fitting def random_graph(n=5000, seed=None): """ Uniformly random point cloud generation. `n` [int] Number of points to generate. Default 5000 seems like a good starting point in point density and corresponding runtime for the subsequent calculations. @return [numpy.ndarray] Array of shape(n, 2) containing the coordinates for each point of the generated point cloud. """ if seed is None: import secrets seed = secrets.randbits(128) rng = np.random.default_rng(seed=seed) return rng.random((n, 2)), seed def spatial_graph(adata): g, pos = graph_tool.generation.triangulation(adata, type="delaunay") g.vp["pos"] = pos weight = g.new_edge_property("double") for e in g.edges(): weight[e] = math.sqrt(sum(map(abs, pos[e.source()].a - pos[e.target()].a)))**2 return g, weight points, seed = random_graph() g, weight = spatial_graph(points) g = GraphView(g) # calculate centrality values vp = closeness(g, weight=weight) vp.a = np.nan_to_num(vp.a) # correct floating point values # ep.a = np.nan_to_num(ep.a) # correct floating point values # calculate convex hull convex_hull = centrality.convex_hull(g) # plot graph with convex_hull fig = plt.figure(figsize=(15, 5)) ax0, ax1 = fig.subplots(1, 2) plot.graph_plot(fig, ax0, g, vp, convex_hull, f"Closeness without prediction") # generate model based on convex hull and associated centrality values quantification = plot.quantification_data(g, vp, convex_hull) # optimize model's piece-wise linear function d = quantification[:, 0] C = quantification[:, 1] m_opt, c0_opt, b_opt, aic_opt = fitting.fit_piece_wise_linear(d, C) vp = centrality.correct(g, vp, m_opt, c0_opt, b_opt) plot.graph_plot(fig, ax1, g, vp, convex_hull, f"Closeness with model prediction") fig.savefig(f"model_prediction_comparison.svg", format='svg')